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dc.contributor.advisorSanders, Christine C.en_US
dc.contributor.authorWilson, Stephen G.en_US
dc.date.accessioned2018-06-20T17:04:04Z
dc.date.available2018-06-20T17:04:04Z
dc.date.issued1976en_US
dc.identifier.urihttp://hdl.handle.net/10504/118429
dc.description.abstractStudies concerning the effects of procedural variations on the activity of aminoglycosides have revealed that a single procedural change can significantly alter results, particularly in tests with Staphylococcus aureus (116,123). Variations in such factors as inoculum and type of medium used may at times also alter the clinical interpretation of results, and significant discrepancies between the minimal inhibitory concentrations and minimal bactericidal concentrations of aminoglycosides have been observed (62,90,116). These observations suggest the presence of a small subpopulation of cells within the sensitive parent strain which are more resistant to the effects of the aminoglycoside. Therefore, the purpose of this study was to (a) evaluate the bactericidal activity of aminoglycosides against Staphylococcus aureus by the use of kill curves (b) characterize the more resistant cells selected from strains of Staphylococcus aureus which appeared to be sensitive to aminoglycosides by minimal inhibitory concentration determinations, and (c) determine the prevalence of strains containing these more resistant cells.en_US
dc.language.isoen_USen_US
dc.publisherCreighton Universityen_US
dc.rightsA non-exclusive distribution right is granted to Creighton University and to ProQuest following the publishing model selected above.en_US
dc.subjectMicrobiologyen_US
dc.titleSelection and Characterization of Strains of Staphylococcus aureus Displaying Unusual Resistance to Aminoglycosidesen_US
dc.typeThesis
dc.publisher.locationOmaha, Nebraskaen_US
dc.description.noteProQuest Traditional Publishing Optionen_US
dc.contributor.cuauthorWilson, Stephen G.en_US
dc.degree.levelMS (Master of Science)en_US
dc.degree.disciplineMedical Microbiology (graduate program)en_US
dc.degree.nameM.S. in Medical Microbiologyen_US
dc.degree.grantorGraduate Schoolen_US


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