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Assessment of Vl30 Erythropoietin Responsive Promoters for Erthyroid Gene Therapy
(Creighton University, 2002-06)
Congenital blood disorders such as hemoglobinopathies and thalassemias are common, and yet clinically challenging glob in disorders. Gene therapy was thought to serve as a therapeutic method to treat these disorders through ...
Cloning and Tissue Distribution of Two NA+/H+ Exchangers from the Malpighian Tubules of Aedes Aegypti
(Creighton University, 2002)
A Na+/H+ exchanger (NHE) on the apical membrane of mosquito Malpighian tubule (MT) cells likely participates in the female blood-feeding mosquito's necessary secretion ofNa+ and fluid. This study presents the molecular ...
Effects of Homocysteine on Cardiac Neural Crest Cell Formation
(Creighton University, 2002)
Elevated homocysteine (Hcys) causes a wide spectrum of congenital detects, many of which resemble neural crest (NC) cell ablation. However, the etiological mechanism is not known. The purpose of this study was to determine ...
Detection of Plasmid-Mediated AmpC b-Lactamases
(Creighton University, 2004-07)
Although plasmid-mediated AmpC b-lactamases were first reported in the late 1980's, most clinical laboratories and physicians remain unaware of their clinical importance. Current detection methods for organisms producing ...
The Na/K-ATPase in the gills of Antarctic and New Zealand nototheniids: The Physiologic and Molecular Effects of Warm-acclimation.
(Creighton University, 2002)
Antarctic fish, living in -2°C waters, have a serum osmolality of « 600mOsm/kg nearly double that of temperate teleosts. The increase in serum osmolality is due to proportional increases in the Na" and CT concentrations ...
Functional Roles of A1-adrenergic Receptors in the Bovine Inferior Alveolar Artery: Regulation of Contraction and Activation of Extracellular Signal Regulated Kinase
(Creighton University, 2002-06)
The bovine inferior alveoiar artery (BIAA) runs inside the length of the mandibie and branches to form dental arteries that supply blood to the teeth. I investigated the effects of 5-hydroxytryptamine (5-HT), acetylcholine ...
Hope from within: Reform in the Islamic Republic and Ayatollah Montazeri's Mission to Fulfill the Promises of the Iranian Revolution
(Creighton University, 2009-05-15)
The primary purpose of this project was to demonstrate the strong degree of support for reform in Iran from within the clergy. Additionally, this study sought an understanding of why the reform movement had failed and ...
Functional Responses of Lung Dendritic Cell Subsets in Flt3 Ligand-Induced Immunomodulation in Allergic Asthma
(Creighton University, 2009-08)
Asthma is an inflammatory airway disease characterized by airway eosinophilia, airway obstruction due to an increased mucus production by goblet cells, airway remodeling, and airway hyperresponsiveness (AHR) to a variety ...
Measuring and Comparing the Diffusion Rate of Fluorescent-Lipophilic-Neurotracing Probes in Murine-Peripheral-Nerve Preparations
(Creighton University, 2009-06-11)
Lipophilic-fluorescent dyes are used as probes to study the neural pathways that wire the brain. Since these dyes are able to define neuroanatomic connections through all stages of normal and mutant development, they are ...
Birth Parent Love Portrayed in Domestic Adoption Children's Literature
(Creighton University, 2008-09-29)
This thesis examines domestic adoption children’s literature published in the 1970’s, 1980’s, and 1990’s, to assess if the authors portrayed birth parent love through narration and/or illustration toward the child relinquished ...