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Evaluation of Concentrations in Penicillin Sensitivity Discs
(Creighton University, 1960)
Since the advent of antibiotics as chemotherapeutic agents, the importance of determining the sensitivity to these drugs of micro-organisms present in clinical specimens has become of prime importance. | Prior to Fleming's ...
Mutation of Coagulase Negative Staphylococcus in the Presence of Human Serum
(Creighton University, 1960)
The Staphylococcus that Pasteur observed in 1880 has until recently been referred to in the literature as Micrococcus pyogenes. In the Seventh Edition of Bergey's Manual this organism has been reclassified into two major ...
Enzyme Mediated Gentamicin Resistance Among Gram-Negative Clinical Isolates
(Creighton University, 1976)
Gentamicin is a broad-spectrum, bactericidal antibiotic of the aminoglycoside family. It has been shown through extensive evaluation to be effective in the treatment of serious gram- negative bacillary infections (1-5). ...
Dermatophyte Respiration Antagonism in Vitro by Juglone
(Creighton University, 1960)
Centuries before juglone was isolated and structurally analyzed it was employed as a medicinal ingredient in combating venereal diseases, eczema, mycotic infections, gastro-intestinal disorders and a number of varied ...
An Epidemiological Evaluation of Antagonism Between the Normal Throat Flora and Group a Streptococci
(Creighton University, 1975)
The epidemiology, treatment, and prevention of group A streptococcal pharyngitis and its sequela of rheumatic fever have been extensively studied. Estimates of the incidence of streptococcal pharyngitis in the United States ...
The Mode of Action of Immunoregulatory Alpha Globulin (IRA) on Murine Lymphocytes: Relation of the Immunosuppressive Activity of Various Pathologic Conditions
(Creighton University, 1974)
Numerous reports in the literature indicate that there are immunosuppressive components in the alpha globulin fractions of human and murine sera (1, 2, 3, 4, 5, 6, 7, 8, 9). These investigations shed new insights on the ...
Furfural and the Treatment of Experimental Histoplasmosis
(Creighton University, 1958)
Histoplasmosis was described over 50 years ago by S. T. Darling while he was a pathologist at Ancon (now Gorgas) Hospital in the Panama Canal Zone (20). During 1905-1906 three patients had entered the hospital terminally ...
The Effect of the Carcinogen 20-methylcholanthrene on the Production of Vaccinal Viral Lesions on the Chorio-Allantoic Membrane of the Embryonated Egg
(Creighton University, 1954)
In the past, a great number of Investigations have been conducted to study the various effects of carcinogenic agents on laboratory animals. Some of the earlier works were devoted to observing the effect of certain carcinogens ...
Plasmid-Host Cell Relationships in Staphylococcus Aureus: The Role of Deoxyribonucleic Acid Dark Repair Systems
(Creighton University, 1977)
Numerous studies have demonstrated the existence of DNA repair systems which function to preserve the basic integrity of genetic material. These repair systems are of two basic classes: the first class contains a repair ...
Inhibition of Proteus Swarming by the Metabolic Products of Serratia Marcescens
(Creighton University, 1971)
Proteus vulgaris and Proteus mirabilis, members of the family Enterobacteriaceae, exhibit the phenomenon of swarming on moist agar media. Swarming is a cyclic pattern of active motility and stationary growth away from a ...