Now showing items 1-4 of 4
Effect of hair cell microRNAs on gene expression profiles of cultured mouse otic precursor cells
(Creighton University, 2011-10-17)
Hearing loss caused by environmental and genetic factors is exacerbated by the inability of mammalian auditory hair cells to spontaneously regenerate. Recent studies demonstrate that mechanosensitive hair cells can be ...
Role of CDC25 Phosphatases in Non-Melanoma Skin Cancer
(Creighton University, 2014-06-19)
Non-melanoma skin cancers, the most common cancers in the United States, result from chronic exposure to ultraviolet irradiation (UV). UV-induced DNA damage activates cell cycle checkpoints through a mechanism involving ...
Immunoregulatory Effects of Vitamin D in Cockroach-induced Asthma
(Creighton University, 2014-08)
Asthma is a chronic inflammatory lung disease of airways associated with reversible airway obstruction, functional and structural changes in the airways, and airway remodeling. Increased infiltration of CD4+ lymphocytes, ...
Bone Response to Cyclooxygenase Inhibition and Mechanical Loading
(Creighton University, 2015-01-08)
Bone is a dynamic tissue constantly adapting to daily mechanical forces. Suppressing the bone’s ability to adapt to increased forces may lead to insufficient strength and ultimately fracture. Non-steroidal anti-inflammatory ...