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Preparation, Characterization and In Vitro Evaluation of Metformin Loaded Hyaluronic Acid Nanoparticles for Oral Delivery
(Creighton University, 2016-07-21)
Metformin, an anti-diabetic drug, has a low oral bioavailability (50-60%) due to its poor intestinal absorption. Orally administered mucoadhesive nanoparticles have been shown to interact with the intestinal mucus layer ...