Search
Now showing items 1-10 of 13
Development of Cochlear Nonlinearities in Normal and Tshr Mutant Mice
(Creighton University, 2005)
Aim - (from the introduction - no abstract provided) |The goal of this project is twofold. The primary goal is to improve our understanding of cochlear development, and the development of cochlear nonlinearity in particular. ...
Molecular Interactions of Basic Helix Loop Helix (bHLH) Genes in Inner Ear Development
(Creighton University, 2005-08-02)
The inner ear originates from an ectodermal thickening, the otic placode, which invaginates and forms the otic vesicle. The otic placode gives rise to the hearing (cochlea) and balance (vestibular) organs, comprising the ...
Structural and Biological Characterization of Antimicrobial Peptides from Rana Sylvatica and Kassina Senegalensis
(Creighton University, 2005-03)
Gene-encoded antimicrobial peptides are an important component of host defense in both invertebrates and vertebrates, ranging from insects to mammals. Although these peptides are usually isolated in high concentrations, ...
Physiological, Biochemical, and Molecular Biological Effects of +4⁰C Acclimation on the Antarctic Teleost Trematomus bernacchii
(Creighton University, 2005)
The Antarctic teleost Trematomus bemacchii lives in the waters surrounding Antarctica which are a constant -1.8°C. As an adaptive property they possess a uniquely high serum osmolality of -600 mOsm kg"1 which is nearly ...
Cellular Mechanisms Underlying the Action of Melatonin in the Suprachiasmatic Nucleus
(Creighton University, 2005)
The pineal hormone melatonin was extracted in 1958 from the bovine pineal gland. Ever since it has received vast popular attention as a hormone with beneficial effects on sleep disorders, jet lag and longevity. Recent ...
Genetic Linkage to Human Height is Identified to 9q22 and Xq24
(Creighton University, 2005-07)
Human height is a highly heritable trait, with heritability generally above 0.75. Segregation analyses in different populations supported existence of major genes accounting for a considerable fraction of height variation. ...
Role of Membrane-Type Matrix Metalloproteinases and Tissue Inhibitor of Metalloproteinase-2 in Neural Crest Cell Migration
(Creighton University, 2005)
During embryonic development, cardiac neural crest {NC) cells arise from the dorsal portion of the neural tube through an epithelial-to-mesenchymal transition and then migrate into the pharyngeal arches and subsequently ...
Genome-wide Linkage Studies for Bone Mineral Density, Areal Bone Size, and Cross-sectional Bone Geometry
(Creighton University, 2005-05)
Osteoporosis is a major public health problem, mainly characterized by compromised bone strength. The bone strength is determined by many skeletal factors, including bone mineral density (BMD), geometric structure, ...
Effect of Smoke Exposure and Ethanol Ingestion on Anti-Pneumococcal Host Defenses
(Creighton University, 2005)
Alcohol abusers and smokers are more susceptible to the development of respiratory tract infections caused by Streptococcus pneumoniae, the pneumococcus.To investigate the effect of smoke exposure and EtOH ingestion on ...
Genome-Wide Linkage Scan and Association Analyses for Obesity Genes
(Creighton University, 2005-08)
Obesity is a condition of excess body fat that causes or exacerbates several major public health problems. Common obesity is a polygenic disorder arising from the interaction of multiple genetic and environmental factors. ...