Now showing items 1-10 of 23
MicroRNAs are essential for hair cell development.
(Creighton University, 2008-10-10)
MicroRNAs are small non-coding RNAs that are processed through an endogenous biological pathway and function to post-transcriptionally regulate target gene expression. MicroRNAs affect cellular proliferation, differentiation, ...
Development and Characterization of Nanoparticulate Delivery System for the Radioprotectant Drug Amifostine
(Creighton University, 2008-05)
Amifostine is a cytoprotectant drug used as an adjunct in cancer chemotherapy and radiation therapy. A simple and sensitive HPLC method was developed and validated for the assay of Amifostine. The method consisted of 95:5 ...
The Effects of Chronic Ethanol Ingestion and Smoke Exposure on Anti-Pneumococcal Host Defenses
(Creighton University, 2008-12)
Individuals who abuse alcohol and tobacco are at increased risk for pneumonia caused by Streptococcus pneumoniae (the pneumococcus). Alcohol and cigarette smoke are known to exert immunosuppressive effects on pulmonary ...
Hybrid Ray Optics and Continuum Mechanics Modeling of Cell Deformation in the Optical Stretcher
(Creighton University, 2008-01-21)
Since the invention of the optical stretcher in 2001, no direct method has been found for measuring the optical stress that produces the observed trapping and stretching of biological cells and other dielectrics. Hence, ...
Political Effects of Remittances: Political Participation in Developing Countries
(Creighton University, 2008-12-04)
In this thesis I propose to analyze the effects of remittances on political participation in the recipient countries. I test two opposing hypotheses. The first hypothesis argues that dependence on remittances results in a ...
Baseball Statistics in the Steroids Era
(Creighton University, 2008-06-27)
This thesis examines the presence of steroids and performance enhancing substances in Major League Baseball from approximately 1988 to 2008. This period, informally known as the “steroids era,” has been the source of great ...
Factors Predicting Public Support or Opposition in Israel for the Creation of a Palestinian State
(Creighton University, 2008-11-14)
In this thesis I discus the ethno-national conflict in Israel. I submit that the conflict is a dangerous one and it should be studied and analyzed in order to provide the International System with better understanding of ...
Angular Correlation of Emitted Neutrons Due to Giant Dipole Resonance in Ultra Peripheral Collisions
(Creighton University, 2008-05-29)
In an ultra peripheral collision with two gold ions, two virtual photons are exchanged, which excites the nuclei into a mutual giant dipole resonance (GDR) state. This excited state decays most often via neutron emission. ...
Upregulation of PIP3-dependent RAC Exchanger 1 (P-Rex1) Promotes Prostate Cancer Metastasis
(Creighton University, 2008-08-18)
Activation of Rac by guanine-nucleotide exchange factors (GEFs) at the leading edge of the cell plays an important role in directional cell migration, a critical step of tumor metastasis cascades. We investigated the role ...
Constructing Minority Governments
(Creighton University, 2008-09-25)