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CD30: A Novel Receptor to Induce Apoptosis in Human Blood Eosinophils
(Creighton University, 2005-05)
Eosinophils are one of the major effector cells in asthma, and controlling the number and survival of eosinophils might attenuate the severity of asthma. This could be achieved by inducing eosinophil apoptosis. Apoptosis ...
Resistance to Apoptosis in Smooth Muscle Cells and Stent-Induced Stenosis in Coronary and Peripheral Arteries
(Creighton University, 2003-02-07)
Occlusive vascular disease is one of the major causes of morbidity and mortality in the United States. Treatment often involves angioplasty and stenting. In 30-50% of angioplasty cases, success is limited by re-narrowing ...
TRAIL and TGF-ßl-Induced Apoptosis of Human Airway Epithelial Cells
(Creighton University, 2006-07)
Asthma is a chronic inflammatory disease characterized by airway hyperresponsiveness (AHR), airway obstruction, wheezing, and leads to airway remodeling if these symptoms persist. Airway remodeling is characterized by ...