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Development and Characterization of Nanoparticulate Delivery System for the Radioprotectant Drug Amifostine
(Creighton University, 2008-05)
Amifostine is a cytoprotectant drug used as an adjunct in cancer chemotherapy and radiation therapy. A simple and sensitive HPLC method was developed and validated for the assay of Amifostine. The method consisted of 95:5 ...
Development and Characterization of Polymeric Nanoparticulate Delivery System for Hydrophillic Drug: Gemcitabine.
(Creighton University, 2009-12)
Gemcitabine is a nucleoside analogue, used in various carcinomas such as non small cell lung cancer, pancreatic cancer, ovarian cancer and breast cancer. The major setbacks to the conventional therapy with gemcitabine ...
Chitosan-hydroxyapatite Drug Delivery System in Root Canal Filling and Delivery
(Creighton University, 2007-01)
A root canal is one of the major components of a tooth. It is a long passage full of soft tissues, deep within thg, dentin of the tooth, adjoining the pulp chamber. The major cause of root canal infection is endodontic ...
In Vitro Evaluation of Antiemetic Topical Gels in Cancer Chemotherapy
(Creighton University, 2007-08)
The objective of this study was to evaluate the diffusivity and the release characteristics of different antiemetics from plurionic gels using various in vitro models (polymeric membrane, skin sheds of Yellow Rat and Com ...