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Surface Modified Solid Lipid Curcumin Nanoparticles For Oral Delivery
(Creighton University, 2011-08)
Curcumin is a naturally available polyphenolic compound that has demonstrated chemotherapeutic effects in several carcinogenic models as well as pre-clinical trials. However, its poor oral bioavailability due to extremely ...
Multifunctional Nanoparticles for Cancer Therapy
(Creighton University, 2014-03-15)
The relapse of cancer after first line therapy with anticancer agents is a common occurrence. This recurrence is generally accepted to be due to the presence of a small subpopulation of cells called cancer stem cells. Thus, ...
Multifunctional Nanoparticles Containing Hydrophilic and Hydrophobic Drugs for Anticancer Drug Delivery
(Creighton University, 2013-07-30)
Combination therapy is routinely used in anticancer therapy for maximizing efficacy and minimizing systemic toxicity. The nanoparticle drug delivery of the hydrophobic paclitaxel with hydrophilic gemcitabine offers the ...