Now showing items 1-10 of 162
The Book of Lost Things
(Creighton University, 2009-05-05)
Adapted from John Connolly's novel The Book of Lost Things
A Contemporary Discussion about the Influence of African Art and Culture on European Art with an Emphasis on Miquel Barceló
(Creighton University, 2009-05-04)
In modern day it is easy to asses where our artistic influences come from. However there are cases when those influences have not been treated with proper respect and have been appropriated with methodologies that have ...
Design, Synthesis and Pharmacological Characterization of Novel Calcitonin Gene-Related Peptide Receptor Antagonists
(Creighton University, 2006-06)
ABSTRACT|Human-a-calcitonin gene-related peptide (CGRP) is a 37 amino acid residue neuropeptide produced from tissue-specific alternative splicing of the primary RNA transcript of the calcitonin gene. CGRP is widely ...
The Influence of ampC Expression and Penicillin Binding Protein Binding on the Variation of ß-lactam Induction Potential in Three Genera of Enterobacteriaceae
(Creighton University, 2006-04-08)
Citrobacter freundii, Enterobacter cloacae, and Serratia marcescens are members of the Enterobacteriaceae family and are significant nosocomial pathogens. These organisms encode inducible, chromosomal AmpC ß-lactamases ...
Genome-Wide Linkage Scan and Association Analyses for Obesity Genes
(Creighton University, 2005-08)
Obesity is a condition of excess body fat that causes or exacerbates several major public health problems. Common obesity is a polygenic disorder arising from the interaction of multiple genetic and environmental factors. ...
Regulation of STAT-1 Phosphorylation by Histamine Through H1 and H2 Receptors: Inverse Agonism and PKA-PKC Interaction in STAT-1 Phosphorylation
(Creighton University, 2005-05-05)
Signal transducer and activator of transcription-1 (STAT1) is a latent signal transducer protein which, on phosphorylation, is translocated from the cytoplasm to the nucleus and is subsequently activated. This work was ...
Rarity of Novel microRNAs in the Mouse Inner Ear
(Creighton University, 2007-11)
The vertebrate inner ear is a complex organ that is highly regulated throughout development by molecular and cellular factors such as morphogens and transcription factors. Another class of gene regulators whose function ...
Preformulation and Formulation Development of a Novel Radioprotectant Drug
(Creighton University, 2007-10)
Onconova 1210.Na (1210) is a chlorobenzylsulfone derivative with potential property to mitigate the effects of accidental or intentional exposure to life threatening levels of radiation. A rapid and sensitive HPLC method ...
Anti-allergic drug and intracellular signaling mechanisms in human blood eosinophils and airway epithelial cells,
(Creighton University, 2006-04-25)
The atopic asthmatic response is very complex and involves various mediators, second messengers and cell types whose roles in the inflammatory response are being elucidated at the present time. Suplatast tosilate (IPD), a ...
Cloning and Tissue Distribution of Two NA+/H+ Exchangers from the Malpighian Tubules of Aedes Aegypti
(Creighton University, 2002)
A Na+/H+ exchanger (NHE) on the apical membrane of mosquito Malpighian tubule (MT) cells likely participates in the female blood-feeding mosquito's necessary secretion ofNa+ and fluid. This study presents the molecular ...