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Now showing items 111-120 of 162
Sequence-Based Molecular Epidemiology of Methicillin-Resistant Staphylococcus aureus
(Creighton University, 2003-12-12)
Methicillin-resistant S. aureus (MRSA) are a major cause of nosocomial infections requiring accurate and rapid molecular techniques for epidemiological analysis. Increased genomic sequence information has resulted in the ...
Biochemical Studies on Uncoupling Proteins and Glucose Metabolism in Skeletal Muscle
(Creighton University, 2002)
Uncoupling protein (UCP) is an inner-mitochondrial membrane protein that uncouples the production of ATP from the electron transport chain, thereby inducing thermogenesis. Recently, a family of UCP homologues was identified, ...
Carotid Atherosclerosis: Why Some Patients are Symptomatic and Others Not?
(Creighton University, 2002-12)
Occlusive vascular disease (OVD) is the leading cause of morbidity and mortality in the United States. OVD of the carotid arteries results in stroke or transient ischemic attacks. A significant number of strokes are caused ...
Prion Strain Diversity and Molecular Properties of PrPsc
(Creighton University, 2003-09-11)
The transmissible spongiform encephalopathies or prion diseases are a group of uniformly fatal neurodegenerative diseases that affect both humans and animals. The agent of these diseases is proposed to consist solely of ...
A Novel IN SITU Gel for Sustained Drug Delivery and Targeting
(Creighton University, 2003-08)
The deacetylated form of chitin known as chitosan is currency been investigated due to its biodegradability, biocompatibility, non-toxic nature and its ability to form in situ gel with pH changes. Chitosan has also been ...
Comparison of Ecto-Nucleotidase Activity in PAR-C5 Cells and Native Rat Parotid Gland
(Creighton University, 2002-12)
Cells from a parotid gland acinar cell line (PAR-C5) cells were investigated to compare the activity of the ecto-nucleotidase enzyme in those cells to those of native parotid gland acinar cells. The object of this study ...
Neurally Released Nitric Oxide does not Oppose Reflex Cholinergic Contraction of Airway Smooth Muscle in Dogs
(Creighton University, 2001)
When afferent nerve endings in the airway detect a foreign substance, centrally mediated reflexes, acting through cholinergic parasympathetic efferents, contract airway smooth muscle. It has been proposed that these efferents ...
Regulation of Vascular Smooth Muscle Cell Apoptosis by Insulin-like Growth Factor-1: Control of Apoptosis Induced by C-MYC and Protein Kinase Inhibition
(Creighton University, 2000-06-15)
The biological actions of insulin-like growth factor-1 (IGF-1) are critical from embryonic development through adulthood. IGF-1 exerts its actions almost exclusively through the IGF-1 receptor (IGF-1 R), perpetuating a ...
Resistance to Apoptosis in Smooth Muscle Cells and Stent-Induced Stenosis in Coronary and Peripheral Arteries
(Creighton University, 2003-02-07)
Occlusive vascular disease is one of the major causes of morbidity and mortality in the United States. Treatment often involves angioplasty and stenting. In 30-50% of angioplasty cases, success is limited by re-narrowing ...
From the Ear to the Brain: Ontogeny of the Primary Vestibular Neurons' Projections
(Creighton University, 2002)
(First paragraph of Introduction)|The development of neural projections and the establishment of functioning neural circuits are crucial developmental events in an animal's life since they underlie both perceptive and ...