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Now showing items 151-160 of 162
The Challenge of Modifying Deviant Behavior: Restructuring Incentives in Renegade Regimes
(Creighton University, 2007-08-23)
This thesis considers whether international coercion used to confront deviant behavior in renegade or rogue regimes produces an offset of the benefits of continued defiant behavior, or produces a restructuring of incentives ...
Zenith Angle Dependence of Prompt Muons in High Energy Cosmic Showers
(Creighton University, 2007-08)
The prompt component of cosmic showers received increasing interest in the last decade because of its potential to expose us to new physics and to help us explore the universe using neutrino telescopes. In this study we ...
Investigation of Prestin Membrane Topology by Substituted Cysteine Accessibility Method.
(Creighton University, 2008-04-23)
Prestin, an integral membrane motor protein in the outer hair cells of the inner ear, is proposed to be crucial for cochlear amplification. In support of this, in prestin knock out mice, there is a 40-60 dB loss of hearing ...
Dynamic Light Scattering in Mixed Alkali Metaphosphate Glass Forming Liquids
(Creighton University, 2008-06-20)
The Mixed alkali effect (MAE) is an often studied phenomenon, 0ccurring in material containing more than one type of alkali, in which a marked deviation from linear compositional dependence is observed. Previous studies ...
Sequence and Structure Specific Cleavage of Cryptic Recombination Signal Sequences by the V(D)J Recombinase
(Creighton University, 2009-12)
Introduction Immune repertoire diversity is largely achieved by a process termed V(D)J recombination, during which functional antigen receptor genes are assembled from discrete gene segments through site-specific DNA ...
The Missing Founding Fathers: The Need to Teach the Role of the Antifederalists in the Adoption of the Bill of Rights
(Creighton University, 2009-12-01)
This thesis examines the need to place more emphasis on teaching the role of the Antifederalists in the 1787-88 debate over the adoption of the U.S. Constitution to high school history and government students. The cited ...
Development and Characterization of Polymeric Nanoparticulate Delivery System for Hydrophillic Drug: Gemcitabine.
(Creighton University, 2009-12)
Gemcitabine is a nucleoside analogue, used in various carcinomas such as non small cell lung cancer, pancreatic cancer, ovarian cancer and breast cancer. The major setbacks to the conventional therapy with gemcitabine ...
Purification of Human Immunodeficiency Virus Type 1 Preintegration Complexes by Velocity Gradient Centrifugation.
(Creighton University, 2009-12-11)
The early events of human immunodeficiency virus type 1 (HIV-1) infection are mediated by two large nucleoprotein complexes (NPCs), the reverse transcription complex (RTC) and the preintegration complex (PIC). These ...
STARlight: A C++ Object-Oriented Monte Carlo Event Generator for Ultra-Peripheral Collisions
(Creighton University, 2009-12-25)
Ultra-peripheral collisions occur when nuclei pass one another without overlapping. The intense electric fields present can be treated as a flux of virtual photons; these photons can interact with the other nucleus or each ...
In vivo Genome-wide Expression Study on Human Blood B cells Suggests a Novel ESRI and MAPK3 Network for Postmenopausal Osteoporosis
(Creighton University, 2007-05)
Osteoporosis is characterized by low BMD resulting from bone resorption (by osteoclasts) exceeding bone formation (by osteoblasts). In postmenopausal women, estrogen deficiency evokes increased osteoclastic activity and ...