This is a collection of patents assigned to Creighton University. The list includes expired as well as current patents.

Please use the browse indexes in the column on the right. Use the search box above to search the entire patent text (including the patent number).

Recent Submissions

  • Seizure Therapy 

    Simeone, Kristina A.; Simeone, Timothy A. (United States Patent Office, 2017-07-11)
    A method and a composition are utilized to affect mitochondrial functions on a seizure-genic brain region. In one aspect, the disclosure comprises methods of treating seizures. Seizures are a transient symptom of abnormal ...
  • Stabilizing Instrumentation for the Performing of Endoscopic Surgical Procedures 

    Filipi, Charles J.; Cornet, Douglas A. (United States Patent Office, 1998-09-29)
    Apparatus and methods are disclosed for percutaneously providing a stabilized platform for performing endoscopic surgery. The disclosed instrumentation includes an endoscope, a fixation catheter, a loop suture, and a rigid ...
  • Systems and Techniques for Minimally Invasive Gastrointestinal Procedures 

    Filipi, Charles J.; Addink, Jason L.; Klopfenstein, Scott D.; Moncur, Aaron B.; Hunt, Timothy B. (United States Patent Office, 2014-12-09)
    A surgical system for performing gastrointestinal procedures is disclosed. The system includes an elongated body defining an endoscope lumen. The body is adapted to be inserted into the esophagus with a proximal end extending ...
  • Tissue Resection Device and Method 

    Filipi, Charles J.; Hunt, Timothy B. (United States Patent Office, 2014-06-17)
    Among other things, embodiments of devices (and parts thereof) are disclosed that can be used in treating Barrett’s esophagus. Embodiments may have a suction cavity or window portion having elongated planar floor and ramped ...
  • Bite Blocks 

    Filipi, Charles J.; Hadley, Michael L. (United States Patent Office, 2014-09-02)
    Bite blocks providing an instrument lumen 62 for use during transoral medical procedures may be made from a material having a Shore D hardness less than 60 for improved patient comfort. An air way lumen 64 may be provide ...
  • Polynucleotides for Use in Treating and Diagnosing Cancers 

    Xiao, Gary G. (United States Patent Office, 2014-09-23)
    The present invention provides methods for increasing sensitivity of cancer cells to an antiestrogen agent, such as a selective estrogen receptor modulator (SERM). The methods include administering to the subject a ...
  • Estrogen Receptors and Methods of Use 

    Wang, Zhao-Yi (United States Patent Office, 2013-12-31)
    The present invention provides isolated polypeptides having an amino acid sequence having at least 70% identity to SEQ ID NO:20, wherein the polypeptide has ER-a36 activity. The invention further provides methods for ...
  • Systems for Minimally Invasive Gastrointestinal Procedures 

    Filipi, Charles J. (European Patent Office, 2013-10-16)
    [Background] [0001] The present invention relates to surgical devices for excising mucosa in the stomach or esophagus and/or for securing portions of the stomach and esophagus together, e.g. to reduce the size of the ...
  • Systems and Techniques for Minimally Invasive Gastrointestinal Procedures 

    Filipi, Charles J.; Klopfenstein, Scott D.; Addink, Jason L. (United States Patent Office, 2014-02-04)
    A surgical system for performing gastroplasty is disclosed. The system includes an elongated body adapted to be inserted into the esophagus with a proximal end extending from a body orifice. A working member includes a ...
  • Self-Healing Dental Composites and Related Methods 

    Gross, Stephen M.; Latta, Mark A. (United States Patent Office, 2014-05-27)
    Dental restorative composites having self-healing capabilities to repair discontinuities in the composite are provided. Dental restorative composites according to the present invention include a microsphere that encapsulates ...
  • System and Methods for Evaluating Efficacy of Appetite-Affecting Drugs 

    Reidelberger, Roger D. (United States Patent Office, 2015-03-10)
    System and methods to evaluate and administer drugs. The present invention instantaneously identifies the effects that drugs, including appetite-affecting agents, have on animals. Data is collected automatically and analyzed ...
  • Bite Block with Airway Mount 

    Filipi, Charles J. (United States Patent Office, 2015-03-10)
    A bite block 20 for use during transoral medical procedures has a main lumen 42 and a side mount 110 for receiving a separately inserted airway 160. The airway 110 may be a commercially available nasopharangeal airway which ...
  • The High Bone Mass Gene of 11Q13.3 

    Carulli, John P.; Little, Randall D.; Recker, Robert R.; Johnson, Mark L. (European Patent Office, 2008-11-19)
    [Field of the Invention] The present invention relates generally to the field of genetics, genomics and molecular biology. More particularly, the invention relates to methods and materials used to isolate, detect and ...
  • Regulating Lipid Levels Via the ZMAX1 or HBM Gene 

    Carulli, John P.; Little, Randall D.; Recker, Robert R.; Johnson, Mark L. (European Patent Office, 2007-07-18)
    [Field of the Invention] The present invention relates generally to the field of genetics, genomics and molecular biology. The present disclosure relates to methods and materials used to isolate, detect and sequence ...
  • Estrogen Receptors and Methods of Use 

    Wang, Zhao-Y (United States Patent Office, 2012-09-11)
    The present invention provides isolated polypeptides having an amino acid sequence having at least 70% identity to SEQ ID NO:20, wherein the polypeptide has ER-a36 activity. The invention further provides methods for ...
  • Mucoadhesive Nanoparticles for Cancer Treatment 

    Dash, Alekha K.; Trickler, William J. (United States Patent Office, 2012-08-14)
    The present invention relates to a pharmaceutical composition which includes nanoparticles. The nanoparticles include a glyceryl monooleate or monolinoleate (or other mono fatty acid ester); a chitosan; and a cancer ...
  • Compositions Derived from Modiolus Modiolus and Methods for Making and Using Same 

    Collin, Peter D.; Adrian, Thomas E. (United States Patent Office, 2008-06-17)
    Disclosed are compositions which include an isolated soft tissue from Modiolus modiolus (“MM”) and compositions which include an oil isolated from MM or a portion thereof. Also disclosed are methods of treating adenocarcinoma ...
  • Device and Method for Detecting Antibiotic Inactivating Enzymes 

    Black, Jennifer A.; Moland, Ellen Smith; Thomson, Kenneth S. (United States Patent Office, 2007-01-23)
    The present invention provides a method of determining the antibiotic susceptibility of a microorganism comprising the following steps. First, a culture of the microorganism whose susceptibility is to be determined is ...
  • Device and Method for Determining Antibiotic Susceptibility 

    Black, Jennifer A.; Moland, Ellen Smith; Thomson, Kenneth S. (United States Patent Office, 2008-02-26)
    The present invention provides a method of determining the antibiotic susceptibility of a microorganism comprising the following steps. First, a culture of the microorganism whose susceptibility is to be determined is ...
  • Use of Hydrogen Sulfide in the Treatment of Eye Diseases 

    Ohia, Sunny E.; Opere, Catherine A.; Zhan, Guilin; Monjok, Emmanuel; Kulkami, Kaustubh; Kouamou, Ghislaine E. (United States Patent Office, 2012-01-10)
    Topical administration of a generator of H2S in biological tissues for the treatment of eye disorders, such as glaucoma. NaHS caused a time-dependent decrease in intraocular pressure in normotensive, conscious albino rabbits ...

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