Now showing items 1-20 of 54

    • Method of Producing an Antibiotic 

      Sanders, W. Eugene, Jr.; Sanders, Christine C. (United States Patent Office, 1975-12-09)
      A process for producing an antibiotic substance, given the name Enocin, is described. The process includes culturing Streptococcus salivarius strain K58 until substantial material having antibacterial activity against ...
    • Neuropeptides of the Tachykinin Family 

      Vaudry, Hubert; Conlon, J. Michael (United States Patent Office, 1994-04-19)
      The invention relates to a peptide, characterized in that it corresponds to the following sequence of amino acids: Xaaj Pro Xaa2 Pro Xaa3 Xaa4 Phe Tyr Giy Leu Met in which aN with N equal to 1, 2, 3 or 4 represents ...
    • Removable Portable Basketball Net 

      Stoyall, Daryl R. (United States Patent Office, 1994-08-16)
      A method of removably securing a basketball net to a basketball basket ring wherein an attachment clip is provided at each loop of a conventional basketball net for securing the net to a conventional basketball basket ring. ...
    • Method of Gene Transfer Using Retrotransposons 

      Hodgson, Clague P. (United States Patent Office, 1994-10-11)
      A process for the transfer and/or expression of any gene into cells, organisms or species is disclosed. The process involves isolating the gene, introducing the gene into a vector comprised of at least one retrotransposon ...
    • Apparatus for Studying the Effects of Compressive and Tensile Bending Strains on Bones 

      Akhter, Mohammed P.; Recker, Robert R. (United States Patent Office, 1995-01-24)
      An apparatus for applying compressive and tensile loads on bones having a frame with a work surface and a stepper motor. The stepper motor is operably connected to a rotational force to linear force converter which is in ...
    • Bicyclic Hexahydroaporphine and 1-Benzyloctahydroisoquinoline Therapeutic Compositions and Processes for Utilizing Said Compositions 

      Roche, Victoria F.; Ohia, Sunny E.; Roche, Edward B. (United States Patent Office, 1996-04-30)
      The invention relates to the method of synthesis of bicyclic hexahydroaporphine compounds which may provide improved therapy for diseases characterized by an increase in intraocular pressure. More specifically, the present ...
    • Anti-Tumor Effects of GNRH-IH 

      Lovas, Sandor; Conlon, J. Michael; Vincze, Borbala; Palyi, Istvan; Gaal, Dezso; Kalnay, Adrienn; Mezo, Imre; Teplan, Istvan; Toth, Geza; Kovacs, Magdolna (United States Patent Office, 1997-01-14)
      The present invention provides a novel pharmaceutical composition for the treatment of breast cancer. Also provided are various methods of treating breast cancer.
    • Adjustable Sideholes Catheter 

      Zhan, Xiao X.; Thorpe, Patricia E. (United States Patent Office, 1997-05-06)
      The present invention provides an adjustable sideholes catheter, comprising an inlying catheter having multiple sideholes on its distal side; and an outlying catheter having an irrigation port on its proximal side. Further ...
    • Method for Treating Neurocardiogenic Syncope 

      Kadri, Nazih N. (United States Patent Office, 1998-01-13)
      The present invention relates to methods for treating neu- rocardiogenic syncope. The method involves administering to a patient an effective amount of a compound having the formula: [See attached Patent Form for ...
    • Stabilizing Instrumentation for the Performing of Endoscopic Surgical Procedures 

      Filipi, Charles J.; Cornet, Douglas A. (United States Patent Office, 1998-09-29)
      Apparatus and methods are disclosed for percutaneously providing a stabilized platform for performing endoscopic surgery. The disclosed instrumentation includes an endoscope, a fixation catheter, a loop suture, and a rigid ...
    • Primers for Use in Detecting Beta-Lactamases 

      Hanson, Nancy D.; Sanders, Christine C.; Ehrhardt, Anton F. (United States Patent Office, 2001-06-05)
      Oliognucleotide primers are provided that are specific for nucleic acid characteristic of certain beta-lactamases. The primers can be employed in methods to identify nucleic acid characteristic of family-specific beta-lactamase ...
    • Pleural Cavity Drainage Device 

      Scott, Walter J. (United States Patent Office, 2001-07-03)
      A device useful for draining fluid from the pleural cavity of a patient includes two enclosed chambers. The first chamber has at its upper end a one-way directional valve. The valve, which is provided with a connector for ...
    • Peptide Antagonists of CGRP-Receptor Superfamily and Methods of Use 

      Smith, D. David; Shankar, Saha; Abel, Peter W. (United States Patent Office, 2001-07-31)
      This invention relates to antagonists of calcitonin gene related peptide and in particular the invention relates to amino terminal modifications to peptides to improve their ability to bind to a member of the CGRP-receptor ...
    • GNRH Analogues with Antitumour Effects and Pharmaceutical Compositions Thereof 

      Lovas, Sandor; Murphy, Richard F.; Toth, Geza; Kalnay, Adrienn; Palyi, Istvan; Turi, Gizella; Vincze, Borbala; Mezom, Imre; Vadasz, Zsolt; Teplan, Istvan; Seprodi, Janos; Mora, Melinda (United States Patent Office, 2003-12-16)
      The present invention provides peptides and pharmacologically active compounds including gonadotropin-releasing hormone (GnRH) analogues according to formulas of the invention, wherein the compounds show an antitumor effect. ...
    • Methods for Inhibiting CGRP Binding 

      Smith, D. David; Saha, Shankar; Abel, Peter W. (United States Patent Office, 2004-06-29)
      This invention relates to antagonists of calcitonin gene related peptide and in particular the invention relates to amino terminal modifications to peptides to improve their ability to bind to a member of the CGRP-receptor ...
    • High Bone Mass Gene of 11Q13.3 

      Carulli, John P.; Little, Randall D.; Recker, Robert R.; Johnson, Mark L. (United States Patent Office, 2004-08-03)
      The present invention relates to methods and materials used to isolate and detect a high bone mass gene and a corresponding wild-type gene, and mutants thereof. The present invention also relates to the high bone mass gene, ...
    • Primers for Use in Detecting Beta- Lactamases 

      Hanson, Nancy D.; Sanders, Christine C.; Ehrhardt, Anton F. (United States Patent Office, 2005-05-17)
      Oliognucleotide primers are provided that are specific for nucleic acid characteristic of certain beta-lactamases. The primers can be employed in methods to identify nucleic acid characteristic of family-specific beta-lactamase ...
    • Primers for Use in Detecting Beta-Lactamases 

      Hanson, Nancy D.; Sanders, Christine C.; Ehrhardt, Anton F. (United States Patent Office, 2005-06-14)
      Oliognucleotide primers are provided that are specific for nucleic acid characteristic of certain beta-lactamases. The primers can be employed in methods to identify nucleic acid characteristic of family-specific beta-lactamase ...
    • Multiplex PCR for the Detection of AmpC Beta-Lactamase Genes 

      Hanson, Nancy D.; Perez, Francisco-Javier P. (United States Patent Office, 2006-05-16)
      Oliognucleotide primers are provided that are specific for nucleic acid characteristic of certain AmpC beta-lactamases. The primers can be employed in methods to detect the presence or absence of an AmpC beta-lactamase ...
    • Device and Method for Detecting Antibiotic Inactivating Enzymes 

      Black, Jennifer A.; Moland, Ellen Smith; Thomson, Kenneth S. (United States Patent Office, 2007-01-23)
      The present invention provides a method of determining the antibiotic susceptibility of a microorganism comprising the following steps. First, a culture of the microorganism whose susceptibility is to be determined is ...