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dc.contributor.authorCarulli, John P.
dc.contributor.authorLittle, Randall D.
dc.contributor.authorRecker, Robert R.
dc.contributor.authorJohnson, Mark L.
dc.date.accessioned2015-05-08T16:27:24Z
dc.date.available2015-05-08T16:27:24Z
dc.date.issued2004-08-03
dc.date.submitted2000-04-05
dc.identifier.urihttp://hdl.handle.net/10504/68598
dc.description.abstractThe present invention relates to methods and materials used to isolate and detect a high bone mass gene and a corresponding wild-type gene, and mutants thereof. The present invention also relates to the high bone mass gene, the corresponding wild-type gene, and mutants thereof The genes identified in the present invention are implicated in bone development. The invention also provides nucleic acids, including coding sequences, oligonucleotide primers and probes, proteins, cloning vectors, expression vectors, transformed hosts, methods of developing pharmaceutical compositions, methods of identifying molecules involved in bone development, and methods of diagnosing and treating diseases involved in bone development. In preferred embodiments, the present invention is directed to methods for treating, diagnosing and preventing osteoporosis.en_US
dc.publisherUnited States Patent Officeen_US
dc.titleHigh Bone Mass Gene of 11Q13.3en_US
dc.typePatent
dc.rights.holderCreighton Universityen_US
dc.rights.holderGenome Therapeutics Corporation
dc.contributor.cuauthorRecker, Robert R.
dc.contributor.cuauthorJohnson, Mark L.
dc.identifier.patentapplnumber09/544398en_US
dc.identifier.patentnumberUS 6770461 B1en_US


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