Estrogen Receptors and Methods of Use
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Inventor(s)
Wang, Zhao-Yi
Creighton Inventor(s)
Wang, Zhao-Yi
Assignee
Creighton University
Creighton University
Application Number
10/591,199
10/591,199
Date of Patent
2010-06-29
Patent Number
US 7745230 B2
US 7745230 B2
Date of Application
2007-06-13
2007-06-13
Metadata
Show full item recordAbstract
The present invention provides isolated polypeptides having an amino acid sequence having at least 70% identity to SEQ ID NO:20, wherein the polypeptide has ER-a36 activity. The invention further provides methods for identifying agents that bind to such polypeptides, methods for detecting such polypeptides, and methods for altering the activity of such polypeptides. Also provided are antibodies that specifically bind to an amino acid sequence depicted at SEQ ID NO: 1, or an immunogenic fragment thereof, and methods for making and using such antibodies.