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    Estrogen Receptors and Methods of Use

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    7745230.pdf (2.690Mb)
    Inventor(s)
    Wang, Zhao-Yi
    Creighton Inventor(s)
    Wang, Zhao-Yi
    Assignee
    Creighton University

    Application Number
    10/591,199

    Date of Patent
    2010-06-29
    Patent Number
    US 7745230 B2

    Date of Application
    2007-06-13

    Metadata
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    Abstract
    The present invention provides isolated polypeptides having an amino acid sequence having at least 70% identity to SEQ ID NO:20, wherein the polypeptide has ER-a36 activity. The invention further provides methods for identifying agents that bind to such polypeptides, methods for detecting such polypeptides, and methods for altering the activity of such polypeptides. Also provided are antibodies that specifically bind to an amino acid sequence depicted at SEQ ID NO: 1, or an immunogenic fragment thereof, and methods for making and using such antibodies.
    URI
    http://hdl.handle.net/10504/68627
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